Melanoma
In Brief
Melanoma is a type of skin cancer that develops from the pigment cells of the skin. What distinguishes it is the combination of how quickly it can spread if untreated, and how favorable the outcome is when detected early. A skin examination with a dermoscope reveals signs that the naked eye has difficulty identifying. If something suspicious is found, a biopsy can be performed in the same visit.
Melanoma develops in the melanocytes - the cells that give skin its color. It is the most dangerous form of skin cancer due to its ability to spread to other organs. Israel has one of the highest melanoma rates globally due to its high UV index. Early detection greatly improves the chances of cure.
Symptoms
- Asymmetry - one half of the mole doesn't match the other
- Border - irregular, ragged, or blurred edges
- Color - uneven color with shades of brown, black, pink, red, or blue
- Diameter - larger than 6mm (pencil eraser size)
- Evolving - the mole is changing in size, shape, or color
Treatment Options
- Surgical excision with appropriate margins
- Sentinel lymph node biopsy for staging
- Mohs surgery for melanoma in situ (lentigo maligna)
- Referral for immunotherapy or targeted therapy when needed
- Comprehensive follow-up and surveillance program
Why Mohs Surgery?
Mohs surgery is used for melanoma in situ, particularly lentigo maligna type on the face. The technique allows precise margin control, especially important for melanoma on sensitive facial areas.
Learn about Mohs SurgeryFrequently Asked Questions
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Read more →This medical content was reviewed and verified by Dr. Yehonatan Kaplan on April 8, 2026